Biochemical organization and biochemical evolution
Lyubarev A.E., Kurganov B.I.
Nanobiology, 1996, v. 4, p. 47-54
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The problems of the origin of life and biochemical evolution are analyzed in the context of the biochemical organization concept proposed by the authors earlier. The traditional view according to which the evolution of biological systems of lower levels preceded the formation of systems of higher levels is criticized. It is suggested that the formation of the cell and biological systems of lower levels (subcellular structures, supramolecular structures, biomacromolecules) occurred in a coordinated manner. Nussinov-Mekler's hypothesis that dust (regolith) grains coated with a lipid shell were cell predecessors and Rudenko's concept of the evolution of elementary open catalytic systems (EOCSs) are modernized. The evolution of EOCSs occupying various compartments of regolith grains resulted in their integration into a system of higher rank where EOCS played the role of standard blocks (the supramolecular structure level). The further evolution occurred by rearrangement of the standard blocks.