THE CONCEPT OF BIOCHEMICAL ORGANIZATION AND PROBLEMS OF BIOCHEMICAL EVOLUTION
A. E. Lyubarev and B. I. Kurganov
Evolutionary Biochemistry and Related Areas of Physicochemical Biology (B.F. Poglazov, B.I. Kurganov, M.S. Kritsky, and K.L. Gladilin, eds). Bach Institute of Biochemistry and ANKO, Moscow, 1995, pp. 127–150
Biological organization is defined as the unity of structure, function and regulation of biological systems. For multilevel hierarchical biological systems, biological organization is represented by the hierarchy of functioning controllable structures. The hierarchy of structural levels predetermines the functional hierarchy and the hierarchy of regulatory mechanisms. Biochemical organization includes the levels of the matter organization starting with the cell and lower. Subcellular and supramolecular structures are considered as distinct levels in the organization of biosystems. This concept is used for analyzing problems of the origin of life and biochemical evolution. The traditional view according to which the evolution of biological systems of lower levels preceded the formation of systems of higher levels is criticized. It is suggested that the formation of the cell and biological systems of lower levels occurred in a coordinated manner. NussinovѕMekler's hypothesis that regolith grains coated with a lipid shell were cell predecessors and Rudenko's concept of the evolution of elementary open catalytic systems (EOCS) are modernized. The evolution of EOCS occupying various compartments of regolith grains resulted in their integration into a system of higher rank where EOCS played the role of standard blocks (the supramolecular structure level). Further evolution occurred by rearrangement of the standard blocks.
Титульный лист | Физико-химическая биология